Borussia Dortmund are set to be without attackers Karim Adeyemi and Julien Duranville for over a month.
Both sustained injuries during the Champions League win over Celtic in midweek and following tests in recent days, the news is not positive with each in line to miss five weeks of action.
“Adeyemi and Duranville will be out for a while,” coach Nuri Sahin told reporters ahead of their trip to the capital to take on Union Berlin on Saturday.
“We don’t expect them to return until after the international break in November and the same applies to Gio Reyna. He’s had a setback.”
However, there is better news in relation to forward Donyell Malen.
“He was ill but we think he’ll be back in training today.”